These are the largest deficits OU has overcome to win a game since at least 1954. It is based on games where OU was losing after one or more of the first three quarters. However, there could be a game where they got down by 10 points or more but were able to tie the game or take the lead in the same quarter. If you find another game not listed here, please contact me.
| Points | Score | QTR | Time | Season | Opponent | Result | ||
|---|---|---|---|---|---|---|---|---|
| 25 | 28-3 | 2 | 11:02 | 2019 | A | #12 Baylor | W | 34-31 |
| 21 | 28-7 | 1 | 1:02 | 2021 | N | #21 Texas | W | 55-48 |
| 21 | 21-0 | 2 | 7:44 | 1981 | A | Kansas State | W | 28-21 |
| 21 | 21-0 | 1 | 3:03 | 1970 | A | Iowa State | W | 29-28 |
| 17 | 17-0 | 2 | 12:14 | 2015 | A | #23 Tennessee | W | 31-24 (2OT) |
| 17 | 17-0 | 2 | 12:14 | 2010 | N | #13 Nebraska | W | 23-20 |
| 17 | 20-3 | 4 | 13:49 | 1983 | A | Oklahoma State | W | 21-20 |
| 15 | 15-0 | 2 | 1977 | H | Vanderbilt | W | 25-23 | |
| 14 | 14-0 | 1 | 6:59 | 2018 | A | Texas Tech | W | 51-46 |
| 14 | 21-7 | 2 | 10:15 | 2017 | A | Kansas State | W | 42-35 |
| 14 | 21-7 | 1 | 2:42 | 2016 | A | #21 TCU | W | 52-46 |
| 14 | 21-7 | 3 | 13:35 | 2014 | A | Texas Tech | W | 42-30 |
| 14 | 17-3 | 2 | 11:19 | 2012 | H | #22 Oklahoma State | W | 51-48 (1OT) |
| 14 | 24-10 | 2 | 1:43 | 2006 | H | Texas Tech | W | 34-24 |
| 14 | 28-14 | 2 | 8:48 | 2004 | A | #22 Texas A&M | W | 42-35 |
| 14 | 24-10 | 3 | 9:00 | 2000 | A | #23 Texas A&M | W | 35-31 |
| 14 | 14-0 | 1 | 8:11 | 2000 | H | #1 Nebraska | W | 31-14 |
| 14 | 21-7 | 2 | 3:19 | 1996 | A | Baylor | W | 28-24 |
| 14 | 14-0 | 3 | 1972 | A | #5 Nebraska | W | 17-14 | |
| 14 | 14-0 | 2 | 1963 | H | Iowa State | W | 24-14 | |
| 14 | 14-0 | 2 | 1963 | H | Clemson | W | 31-14 | |
| 14 | 14-0 | 3 | 1961 | A | Nebraska | W | 21-14 | |
| 14 | 14-0 | 2 | 1955 | H | #14 Colorado | W | 56-21 | |
| 13 | 13-0 | 2 | 14:49 | 2013 | A | Kansas | W | 34-19 |
| 13 | 20-7 | 3 | 1973 | H | #17 Miami (FL) | W | 24-20 | |
| 13 | 19-6 | 3 | 1956 | A | Colorado | W | 27-19 | |
| 11 | 21-10 | 4 | 14:12 | 2024 | A | Auburn | W | 27-21 |
| 11 | 14-3 | 1 | 6:00 | 2011 | H | Missouri | W | 38-28 |
| 11 | 14-3 | 2 | 1:43 | 2002 | N | #3 Texas | W | 35-24 |
| 11 | 28-17 | 3 | 1997 | H | Syracuse | W | 36-34 | |
| 11 | 24-13 | 4 | 1996 | N | #25 Texas | W | 30-27 (1OT) | |
| 10 | 17-7 | 3 | 1:30 | 2021 | A | Kansas | W | 35-23 |
| 10 | 10-0 | 2 | 2001 | H | Texas A&M | W | 31-10 | |
| 10 | 10-0 | 2 | 1998 | H | Texas Tech | W | 20-17 | |
| 10 | 10-0 | 3 | 1998 | A | Baylor | W | 28-16 | |
| 10 | 13-3 | 2 | 1995 | A | Iowa State | W | 39-26 | |
| 10 | 17-7 | 4 | 1994 | A | Kansas | W | 20-17 | |
| 10 | 17-7 | 3 | 1986 | A | #5 Nebraska | W | 20-17 | |
| 10 | 10-0 | 3 | 1983 | A | Hawaii | W | 21-17 | |
| 10 | 10-0 | 2 | 1983 | A | Kansas State | W | 29-10 | |
| 10 | 10-0 | 2 | 1981 | H | Wyoming | W | 37-20 | |
| 10 | 10-0 | 2 | 1980 | A | #4 Nebraska | W | 21-17 | |
| 10 | 10-0 | 2 | 1977 | A | Missouri | W | 21-17 | |
| 10 | 17-7 | 4 | 1976 | A | #10 Nebraska | W | 20-17 | |
| 10 | 17-7 | 2 | 1973 | H | Iowa State | W | 34-17 | |
| 10 | 24-14 | 4 | 1970 | A | Kansas | W | 28-24 | |